In vitro study of LDL transport under pressurized (convective) conditions.

The role of apoptosis in LDL transport through cultured endothelial cell monolayers.

We have previously shown that leaky junctions associated with dying or dividing cells are the dominant pathway for low density lipoprotein (LDL) transport under convective conditions, accounting for more than 90% of the transport [Cancel LM, Fitting A, Tarbell JM. In vitro study of LDL transport under pressurized (convective) conditions. Am J Physiol Heart Circ Physiol 2007;293:H126-32]. To exp...

Effect of endothelial integrity, transmural pressure, and time on the intimal-medial uptake of serum 125I-albumin and 125I-LDL in an in vitro porcine arterial organ-support system.

This report describes a new in vitro, metabolically supported, Sinclair Research Farm minipig aortic preparation in which the intimal-medial uptakes (M, mg.cm-2 of intimal surface) of porcine 125I-albumin and normocholesterolemic (nonoxidized) porcine 125I-low density lipoprotein (LDL) from a stirred, autogenous serum (containing a 125I-protein concentration of c0, mg.cm-3 at 37 degrees C and p...

The role of mitosis in LDL transport through cultured endothelial cell monolayers

Cancel LM, Tarbell JM. The role of mitosis in LDL transport through cultured endothelial cell monolayers. Am J Physiol Heart Circ Physiol 300: H769–H776, 2011. First published December 17, 2010; doi:10.1152/ajpheart.00445.2010.—We (7) have previously shown that leaky junctions associated with dying or dividing cells are the dominant pathway for LDL transport under convective conditions, account...

Sealing of Rotary Drums for Operation Under Pressurized Conditions

Constriction Scour In Pressurized Flow Condition (RESEARCH NOTE)

When depth of flow past a river bridge exceeds opening under the bridge, the flow under the bridge becomes pressurized. The water is directed downward and under the bridge deck, causing increase in velocity and shear stress on the bed thereby increasing bed scour. This is termed as Pressure Flow Scour. The present study investigates the phenomenon of pressure flow scour resulting from a submerg...